• Weizhong Ding, Shirong Chen, Xuexiang Shi, and Yang Zhao.
• Department of Orthopedic Surgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
• Medicine (Baltimore). 2021 May 21; 100 (20): e25850e25850.

BackgroundAnkylosing spondylitis is a recurrent autoimmune disease, which has a high disability rate and seriously affects patients' daily life. Conventional treatment cannot effectively solve the clinical problems of patients, and long-term medication is accompanied by adverse reactions. The evidence shows that warming needle moxibustion has advantages in the treatment of ankylosing spondylitis, but there is still a lack of clinical studies on warm acupuncture alone and long-term follow-up.MethodsThis is a prospective randomized controlled trial to study the efficacy and safety of needle warming through moxibustion in the treatment of ankylosing spondylitis. It was approved by the Ethics Committee of Clinical Research of our hospital. Patients were randomly assigned to an observation group or a control group. The patients were followed up for 6 months after 30 days of treatment. Observation indicators include; activity index, functional ability, Bath Ankylosing Spondylitis Metrology Index, inflammatory indicators, adverse reactions, and so on. Finally, SPASS 22.0 software is used for statistical analysis of the data.DiscussionThis study will evaluate the clinical efficacy of warming needle moxibustion in the treatment of ankylosing spondylitis. The results of this study will provide a reference basis for the clinical use of warm needle moxibustion in the treatment of ankylosing spondylitis.Trial RegistrationOSF Registration number: DOI 10.17605/OSF.IO/GWPX3.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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