• Yun Li and Jung Wang.
• Department of Thoracic Surgery, People's Hospital of Peking University, Beijing, China.
• J Surg Oncol. 2012 Sep 15; 106 (4): 431-5.

ObjectiveTo compare outcomes between thoracoscopic and thoracotomy lobectomy for patients with cN0-pN2 NSCLC.MethodsOne hundred eighty-two cN0 patients (including 29 pN2) underwent VATS lobectomy between September 2006 and December 2009, and 204 cN0 patients (including 47 pN2) underwent thoracotomy lobectomy between July 2000 and December 2009. Pre- and intraoperative status and postoperative survival between two groups were compared.ResultsThere was no difference in preoperative conditions between two groups except Quantity of smoking. Operation time and blood loss of VATS group was significantly lower than thoracotomy group. Number of dissected lymph node (LN) stations was 3.3 ± 1.1 in VATS group versus 3.3 ± 1.3 in thoracotomy group, and the total number of LN was 12.7 ± 8.9 in VATS group versus 10.5 ± 7.2 in thoracotomy group. One- and 3-year disease-free survival rate was 82.6% in VATS group versus 72.0% in thoracotomy group, and 49.3% in VATS group versus 51.3% in thoracotomy group (P=0.996). One- and 3-year survival rate was 84.9% in VATS group versus 71.2% in thoracotomy group, and 64.0% in VATS group versus 42.7% in thoracotomy group (P=0.121).ConclusionsVATS lobectomy is comparable with thoracotomy in both safety and curability for the treatment of cN0-pN2 NSCLC, without necessity of conversion to open surgery.Copyright © 2012 Wiley Periodicals, Inc.

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