• Viviana Lo Buono, Maria Cristina De Cola, Marcella Di Cara, Daniela Floridia, Lilla Bonanno, Simona De Salvo, Francesco Cerra, Cecilia Cannistraci, Giuseppa Maresca, Placido Bramanti, Silvia Marino, and Francesco Corallo.
• IRCCS Centro Neurolesi "Bonino-Pulejo", Messina, Italy.
• Medicine (Baltimore). 2021 May 21; 100 (20): e25920e25920.

AbstractAnxiety and depression are often symptoms present in people who suffer from chronic pain, compromising the quality of life of these individuals. The objective of this study was to assess whether a pulsed radiofrequency (PRF) treatment, in addition to psychological support intervention, can decrease chronic pain, thereby improving quality of life and restoring psychological well-being.Fifty outpatients with a diagnosis of chronic pain, without any benefit from traditional drug therapies, were selected to perform a PRF treatment in combination with a psychological intervention. They were evaluated before and after the intervention through the Hamilton Anxiety Rating Scale and the Beck Depression Inventory-II for anxiety and depression symptomatology, respectively, the Short Form Health Survey 36 (SF-36) was used to assess the subject's quality of life, and the Numerical Rating Scale was used for pain assessment.The Wilcoxon signed-rank test showed a significant difference in Beck Depression Inventory-II (P < .001), Hamilton Anxiety Rating Scale (P < .01), and Numerical Rating Scale (P = .004). In the SF-36 scores, we observed a significant difference between T0 and T1 in both mental (P < .001) and physical (P < .001) dimensions.This study shows that a chronic pain reduction leads to a decrease of anxiety-depressive symptoms and an improvement in quality of life. PRF seems to be an appropriate method to reduce the chronic pain that influences psychological well-being and quality of life.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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