• J Foot Surg · Jan 1983

    Case Reports

    Nitrous oxide-induced myeloneuropathy.

    • J M Lunsford, M H Wynn, and W H Kwan.
    • J Foot Surg. 1983 Jan 1; 22 (3): 222-5.

    AbstractA disabling peripheral myeloneuropathy developed in a health professional with a history of chronic exposure and abuse of nitrous oxide. The distinctive clinical symptoms were radicular sensory loss rather than purely distal, and a "reverse" Lhermitte's sign in the absence of signs of specific spinal cord involvement. The entity of nitrous oxide-induced myeloneuropathy is discussed with a review of the literature, as well as present information regarding the etiology, pathophysiology, symptoms, and treatment. In addition, a case report of nitrous oxide-induced myeloneuropathy is presented.

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