• Linda E Francis, Georgios Kypriotakis, Elizabeth E O'Toole, and Julia Hannum Rose.
• Department of Criminology, Anthropology and Sociology, RT1736, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH, 44115, USA. l.e.francis@csuohio.edu.
• Support Care Cancer. 2016 Sep 1; 24 (9): 3987-96.

PurposeThis study drew on life course theory to argue that the strains of cancer caregiving and bereavement are modified by the age of the patient. We expected that caregivers of middle-aged patients would be more distressed than caregivers of older patients.MethodsThis panel study conducted 199 interviews with family caregivers of advanced cancer patients; first following diagnosis and again shortly after the patient's death.ResultsAmong caregivers of middle-aged patients (40-59), grief mediated the relationship between baseline caregiving and bereavement depressed mood, with grief increasing risk of depression in bereavement. Among caregivers of young-old patients (60-79), grief had a suppressor effect on the relationship between caregiving and bereavement depressed mood, showing greater distress during caregiving than at bereavement.ConclusionsCaregiving for middle-aged cancer patients may increase the risk for severe grief and depression, whereas caregivers of young-old cancer patients appeared to experience relief at bereavement. After bereavement, continued observation may be warranted for caregivers of a middle-aged patient; grief, added to the ongoing demands of their lives (which may include those left behind by a middle-aged patient), may put such caregivers at risk for greater psychological and emotional distress.

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