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Neuropsych Dis Treat · Jan 2015
ReviewPituitary dysfunction following traumatic brain injury: clinical perspectives.
- Fatih Tanriverdi and Fahrettin Kelestimur.
- Department of Endocrinology, Erciyes University Medical School, Kayseri, Turkey.
- Neuropsych Dis Treat. 2015 Jan 1; 11: 1835-43.
AbstractTraumatic brain injury (TBI) is a well recognized public health problem worldwide. TBI has previously been considered as a rare cause of hypopituitarism, but an increased prevalence of neuroendocrine dysfunction in patients with TBI has been reported during the last 15 years in most of the retrospective and prospective studies. Based on data in the current literature, approximately 15%-20% of TBI patients develop chronic hypopituitarism, which clearly suggests that TBI-induced hypopituitarism is frequent in contrast with previous assumptions. This review summarizes the current data on TBI-induced hypopituitarism and briefly discusses some clinical perspectives on post-traumatic anterior pituitary hormone deficiency.
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