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Controlled Clinical Trial
Effect of isoflurane anesthesia on hemodynamics following the administration of an angiotensin-converting enzyme inhibitor in cats.
- Yumi Ishikawa, Masami Uechi, Ryoukichi Ishikawa, Yoshito Wakao, and Sei-ichi Higuchi.
- Ishikawa Animal Hospital, Yokosuka, Kanagawa, Japan.
- J. Vet. Med. Sci. 2007 Aug 1; 69 (8): 869-71.
AbstractThe objective of this study was to evaluate the hemodynamics of the anesthetic isoflurane in healthy cats given angiotensin-converting enzyme inhibitor (ACEI). The 7 healthy young cats and 3 old cats were received placebo or enalapril 0.5 mg/kg orally. The change in systolic arterial pressure from the baseline to 30 min postanesthesia in the ACEI group was significantly higher than in the placebo group (mean +/- SD: -39 +/- 13% vs. -17 +/- 12%, respectively). The present study indicated that general anesthesia may induce hypotension after the administration of an ACEI.
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