• The Journal of pediatrics · Dec 1992

    Case Reports

    Treatment of peripheral tissue ischemia with topical nitroglycerin ointment in neonates.

    • A F Wong, L M McCulloch, and A Sola.
    • Division of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco 94143-0622.
    • J. Pediatr. 1992 Dec 1; 121 (6): 980-3.

    AbstractFour neonates had resolution of peripheral tissue ischemia after the application of 2% nitroglycerin ointment. A dosage of 4 mm nitroglycerin ointment per kilogram of body weight was applied to two patients with ischemia caused by vasospasm from indwelling radial artery catheterization and to two patients with ischemia resulting from dopamine extravasation. No adverse effects were noted except mild episodes of decreased blood pressure in two of the patients.

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