• American heart journal · Dec 2007

    The effect of leisure-time physical activity on the presence of metabolic syndrome in patients with manifest arterial disease. The SMART study.

    • Beate G Brouwer, Frank L J Visseren, Yolanda van der Graaf, and SMART Study Group.
    • Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands.
    • Am. Heart J. 2007 Dec 1; 154 (6): 1146-52.

    BackgroundPhysical activity can influence insulin sensitivity and metabolic syndrome (MetS) independent of weight loss. Therefore, we investigated the independent effect of leisure-time physical activity on the prevalence of MetS and insulin resistance in patients with manifest arterial disease and the role of body fat and fat distribution on this relationship.MethodsData were collected from the Second Manifestations of ARTerial disease study, an ongoing prospective cohort study of patients with manifest vascular disease or vascular risk factors at the University Medical Center Utrecht. Data of 1097 patients, mean age 58.3 +/- 10.4 years, with clinically manifest arterial disease were used. Information on leisure-time physical activity (sporting or other physical exercise) during the past year was collected using a questionnaire. Patients were classified according to the time spent doing leisure-time physical activities: 0 metabolic equivalent (MET)/h per week (64%), 1.0 to 14.9 MET/h per week (16%), and >15.0 MET/h per week (20%).ResultsThe prevalence of MetS was markedly lower (20%) in physically active patients (>15 MET/h per week active) than in physically inactive patients (36%; odds ratio [OR] 0.50, 95% confidence interval [CI] 0.33-0.75) after adjustment for age, sex, body mass index, and smoking. After adjustment for age, sex, waist circumference, and smoking, the OR of having MetS remained essentially the same (OR 0.59, 95% CI 0.38-0.90). Patients who were active (>15 MET/h per week active) had a considerable lower risk of insulin resistance (homeostasis model assessment determined insulin resistance >2.38) than inactive patients (OR 0.40, 95% CI 0.25-0.64) after adjustment for age, sex, body mass index, and smoking.ConclusionsPatients with manifest arterial disease who are physically active are less likely to have MetS and insulin resistance than physically inactive patients, although body weight is comparable between the groups.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.