• Clinical nuclear medicine · Apr 2015

    Case Reports

    Anthracosis mimicking mediastinal lymph node metastases with 18F-FCholine in high-risk prostate cancer.

    • Jean-Baptiste Pinaquy, Philippe Fernandez, Gilles Pasticier, Marie Parrens, and Henri De Clermont.
    • From the *Service de Médecine Nucléaire, Hôpital Pellegrin, CHU Bordeaux, Bordeaux; †INCIA, UMR CNRS 5287, université Bordeaux Segalen, Bordeaux; ‡Service d'Urologie, Hôpital Pellegrin, CHU Bordeaux, Bordeaux; and §Service d'anatomopathologie, Hôpital du Haut-Lévêque, CHU Bordeaux, Bordeaux, France.
    • Clin Nucl Med. 2015 Apr 1; 40 (4): e253-4.

    AbstractA 62-year-old patient with prostate adenocarcinoma underwent PET with radiolabeled choline (18F-Fcholine) for pretreatment staging of a high-risk prostate cancer. Images showed a significant mediastinal lymph node uptake of 18F-Fcholine. Owing to the rarity of spread to supradiaphragmatic lymph nodes, a surgical removal was performed, revealing anthracosis and no malignant cells. Even if its specificity seems better than 18F-FDG, false positives have been reported and other pathologies could mimic lymph node metastases. Consequently, histology should be performed so that the appropriate treatment can be initiated.

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