• Nurs. Clin. North Am. · Mar 2016

    Review

    Blood Transfusion Strategies for Hemostatic Resuscitation in Massive Trauma.

    • Caroline McGrath.
    • School of Nursing, Vanderbilt University, Nashville, TN, USA. Electronic address: caroline.mcgrath@vanderbilt.edu.
    • Nurs. Clin. North Am. 2016 Mar 1; 51 (1): 83-93.

    AbstractMassive transfusion practices were transformed during the 1970s without solid evidence supporting the use of component therapy. A manual literature search was performed for all references to the lethal triad, acute or early coagulopathy of trauma, fresh whole blood, and component transfusion therapy in massive trauma, and damage control resuscitation. Data from recent wars suggest traditional component therapy causes a nonhemostatic resuscitation worsening the propagation of the lethal triad hastening death. These same studies also indicate the advantage of fresh whole blood over component therapy even when administered in a 1:1:1 replacement ratio. Published by Elsevier Inc.

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