• Neuro-Signals · Jan 2005

    Review

    Spinal cord injury: a model of central neuropathic pain.

    • Robert P Yezierski.
    • Comprehensive Center for Pain Research and the McKnight Brain Institute University of Florida, Gainesville, FL 32610, USA. ryezierski@dental.ufl.edu
    • Neurosignals. 2005 Jan 1; 14 (4): 182-93.

    AbstractThe condition of pain after spinal cord injury (SCI) affects the life quality of nearly 70% of individuals with SCI. Clinical studies over the past decade have provided important insights into the complexities of the clinical and psychosocial characteristics of this debilitating consequence of SCI. The use of experimental models developed to study at-level or below-level pain has provided an appreciation for the mechanism(s) responsible for the onset and progression of these conditions. Important to the studies related to SCI pain has been the focus on the molecular, biochemical, anatomical, and functional consequences of SCI that have identified potential therapeutic targets for the design of novel treatment strategies.Copyright 2005 S. Karger AG, Basel

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