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Zhonghua Shao Shang Za Zhi · Jul 2019
Review[Advances in the research of persistent inflammation-immunosuppression-catabolism syndrome in severe burn].
- H Fang, L Xu, and F Zhu.
- Burn Institute of PLA, Department of Burn Surgery, the First Affiliated Hospital, Naval Medical University, Shanghai 200433, China.
- Zhonghua Shao Shang Za Zhi. 2019 Jul 20; 35 (7): 548-551.
AbstractPersistent inflammation-immunosuppression-catabolism syndrome (PICS) is a clinical syndrome in patients surviving from severe trauma or sepsis, which is characterized by prolonged stays in intensive care unit, persistent inflammation response, immune suppression, high protein catabolism, and high mortality. This article aims to review the proposed process of the concept, the mechanism, the clinical features, and the diagnosis and treatment progress of PICS, which is helpful for further understanding pathogenesis and pathophysiological mechanism of PICS in patients with severe burns and improving clinical curative efficacy and prognosis of patients with severe burns.
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