• Zhi-Cheng Deng, Wen-Zhu Jiang, Xiao-Dong Tang, Shuang-Hai Liu, Lei Qin, and Hai-Xin Qian.
• Department of Hepatobiliary Surgery, The First Hospital Affiliated Soochow University, Suzhou 215006, Jiangsu Province, China; Department of Hepatobiliary Surgery, Jiangyin People's Hospital, Jiangyin 214400, Jiangsu Province, China. Electronic address: angelmancity@126.com.
• Int J Surg. 2018 Aug 1; 56: 203-207.

BackgroundThe aim of this study was to investigate the long-term outcomes and perioperative outcomes of laparoscopic hepatectomy (LH) versus open hepatectomy (OH) for hepatocellular carcinoma (HCC) between well-matched patient groups.MethodsWe retrospectively reviewed data from 1535 hepatocellular carcinoma patients who underwent liver resection between January 2002 and December 2016 at two Chinese centres. Propensity score matching of patients in a ratio of 1:1 was conducted and 157 patients were matched.ResultsThe median blood loss (150 vs 380 ml, P < 0.001) was significantly less with LH. The laparoscopic group had shorter hospital stay (6 vs 10 days, P < 0.001) and less complication rate (6.4% vs 24.2%,P < 0.001). There were no significant differences in overall survival and disease-free survival between LH and OH. There were no significant differences in perioperative and long-term outcomes.ConclusionLaparoscopic hepatectomy is technically feasible and safe in selected patients. LH showed similar long-term outcomes, associated with less blood loss, shorter hospital stay, and fewer postoperative complications in selected patients with HCC compared with OH.Copyright © 2018 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

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