• J Clin Med · Jul 2020

    Review

    Diagnostic and Therapeutic Management of Upper Extremity Deep Vein Thrombosis.

    • Floris T M Bosch, NisioMarcello DiMDDepartment of Medicine and Ageing Sciences, Gabriele D'Annunzio University, Via dei Vestini 31, 66100 Chieti, Italy., Harry R Büller, and Nick van Es.
    • Department of Internal Medicine, Tergooi Hospitals, 1213 XZ Hilversum, The Netherlands.
    • J Clin Med. 2020 Jul 1; 9 (7).

    AbstractUpper extremity deep vein thrombosis (UEDVT) accounts for 5% of all deep vein thromboses (DVTs). UEDVT may be complicated by post thrombotic syndrome and pulmonary embolism, and early recognition and prompt start of anticoagulant treatment are key. Primary UEDVT, also known as Paget-von Schrötter syndrome, is associated with repeated or sudden physical activity of the upper arm and venous outflow obstruction due to anatomical variations. Secondary UEDVT is often associated with malignancy or use of intravenous devices, such as central venous catheters or pacemaker leads. Although the diagnosis and treatment of UEDVT have many similarities with DVT of the lower extremities, knowledge of specific aspects regarding UEDVT is important to guide optimal management. In this review, we will discuss the epidemiology, diagnosis, and treatment of UEDVT based on the current literature.

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