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Comparative Study
Systemic absorption of sulphadiazine, silver sulphadiazine and sodium sulphadiazine through human burn wounds.
- H Aoyama, K Yokoo, and K Fujii.
- Department of Plastic Surgery, Aichi Medical University, Japan.
- Burns. 1990 Jun 1; 16 (3): 163-5.
AbstractSystemic absorption of water-soluble and water-insoluble drugs through human burn wounds was compared. Serum levels of sulphadiazine were estimated after application of silver sulphadiazine (water-insoluble) cream, sulphadiazine (water-insoluble) cream and sodium sulphadiazine (water-soluble) cream. It was found that the absorption of sodium sulphadiazine was greater than that of sulphadiazine or silver sulphadiazine.
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