• Internal medicine · Dec 2021

    Review Case Reports

    Clinical Features of Fibrosing Mediastinitis in Japanese Patients: Two Case Reports and a Literature Review.

    • Yoichi Kobayashi, Takashi Ishiguro, Yotaro Takaku, Naho Kagiyama, Yoshihiko Shimizu, and Noboru Takayanagi.
    • Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.
    • Intern. Med. 2021 Dec 1; 60 (23): 376537723765-3772.

    AbstractFibrosing mediastinitis (FM) is a rare fibroinflammatory disease of the mediastinum with an etiology and clinical features that vary by world region. The characteristics of FM in Japan are still unknown. We herein report two Japanese patients with FM who were treated with corticosteroids and responded well. We also reviewed the Japanese literature on PubMed® and summarized the characteristics of 27 Japanese FM patients, including our two patients. In Japan, the predominant cases were those without a specific cause, were diffusely distributed, and responded well to corticosteroid therapy.

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