• Internal medicine · Nov 2021

    Case Reports

    Hemolytic Anemia in a Patient with Subacute Bacterial Endocarditis by Cardiobacterium hominis: A Case Report.

    • Motohiro Shingu, Naoto Ishimaru, Jun Ohnishi, Shimpei Mizuki, Yohei Kanzawa, Kei Kawano, Takahiro Nakajima, Nobuya Sano, and Saori Kinami.
    • Department of General Internal Medicine, Akashi Medical Center, Japan.
    • Intern. Med. 2021 Nov 1; 60 (21): 3489-3495.

    AbstractHemolytic anemia is a rarely occurring manifestation of native valve infective endocarditis. We herein report an afebrile patient with hemolytic anemia caused by Cardiobacterium hominis endocarditis. A 60-year-old Japanese man had a history of aortic root replacement and the gradual onset of general fatigue. He had hemolytic anemia. Blood cultures detected C. hominis. A transthoracic echocardiogram showed aortic valve vegetation and periannular abscess with perforation of the non-coronary cusp. Intravascular hemolysis recovered after antimicrobial therapy, surgical removal of the vegetation and abscess, and aortic valve replacement. Subacute endocarditis should be considered if patients develop hemolytic anemia with signs of chronic inflammation without a fever.

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