• Adnan Bayram, Ayşe Ulgey, Işın Güneş, Ibrahim Ketenci, Ayşe Capar, Aliye Esmaoğlu, and Adem Boyacı.
• Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia. Electronic address: adnanbayram@erciyes.edu.tr.
• Rev Bras Anestesiol. 2015 Jan 1; 65 (1): 61-7.

Background And ObjectivesIt is crucial to decrease bleeding during functional endoscopic sinus surgery. Our primary goal was to investigate the effects of magnesium sulfate and dexmedetomidine used for controlled hypotension on the visibility of the surgical site.Methods60 patients aged between 18 and 65 years were enrolled. In the magnesium sulfate group (Group M), patients were administered 40mg/kg magnesium sulfate in 100mL saline solution over 10min as the intravenous loading dose 10min before induction, with a subsequent 10-15mg/kg/h infusion during surgery. In the dexmedetomidine group (Group D), patients were administered 1μg/kg dexmedetomidine in 100mL saline solution as the loading dose 10min before surgery and 0.5-1μg/kg/h dexmedetomidine during surgery. Deliberate hypotension was defined as a mean arterial pressure of 60-70mmHg.ResultsBleeding score was significantly decreased in Group D (p=0.002). Mean arterial pressure values were significantly decreased in Group D compared to that in Group M, except for the initial stage, after induction and 5min after intubation (p<0.05). The number of patients who required nitroglycerine was significantly lower in Group D (p=0.01) and surgeon satisfaction was significantly increased in the same group (p=0.001). Aldrete recovery score ≥9 duration was significantly shorter in Group D (p=0.001). There was no difference between the two groups in terms of recovery room verbal numerical rating scale.ConclusionsDexmedetomidine can provide more effective controlled hypotension and thus contribute to improved visibility of the surgical site.Copyright © 2014 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

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