• Yasin Sahin, Ozlem Gubur, and Emine Tekingunduz.
• Clinics of Pediatric Gastroenterology, Mersin City Training and Research Hospital, Mersin, Turkey. ysahin977@gmail.com.
• Arch Argent Pediatr. 2020 Jun 1; 118 (3): e241-e245.

IntroductionHP causes local inflammation in the stomach and a systemic humoral immune response. No relationship was found in adult studies investigating the association between HP infection and neutrophil/lymphocyte ratio (NLR) and mean platelet volume (MPV). To our knowledge, there is no study in children. We aimed to evaluate the association between NLR and MPV values with HP infection, severity classification, and pre- and post-treatment status.Population And MethodsPatients with dyspepsia aged between 2-18 years and without any chronic diseases undergoing gastroduodenoscopy were included in the study. Endoscopic mucosal biopsy was performed, HP presence and infection severity were determined according to Sydney Classification.Results153 patients with HP positivity and 211 patients with HP negativity were included in the study, the mean age of them was 13.3 ± 3.4 years and 13.1 ± 3.5 years, respectively. No statistically significant difference was found between patients with HP positive and negative patients and also between severity subgroups of HP positive patients in terms of NLR and MPV (p > 0.05).ConclusionsThere was no association between NLR and MPV values with HP infection, severity classification, or pre- and post-treatment status.Sociedad Argentina de Pediatría.

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