• Ryan Lee, Danny Lee, Pradip Ramamurti, Safa Fassihi, Jessica H Heyer, Monica Stadecker, Michael Webber, Alice Hughes, and Rajeev Pandarinath.
• The George Washington University School of Medicine and Health Sciences, The George Washington University in Washington, 2300 M St, Washington, DC, 20037, USA. ryanlee@gwmail.gwu.edu.
• Eur J Trauma Emerg Surg. 2022 Dec 1; 48 (6): 456945764569-4576.

PurposeOpen reduction and internal fixation (ORIF) are commonly utilized for the repair of distal radius fractures (DRF). While general anesthesia (GA) is typically administered for ORIF, recent studies have also demonstrated promising results with the usage of regional anesthesia (RA) in the surgical treatment of distal radius fractures. This study will compare complication rates between the use of RA versus GA for ORIF of DRFs.MethodsA multi-institutional surgical registry was utilized to identify patients who had undergone ORIF for DRFs from 2005 to 2018-these patients were stratified into GA and RA cohorts. Patients were matched utilizing coarsened-exact-matching (CEM) to compare postoperative outcomes and rates of 30-day complications were compared between the two cohorts.ResultsUpon CEM-matching, 1191 patients receiving RA were matched to 9250 patients who had received GA, with a multivariate imbalance measure (L1) statistic of < 0.001. In the matched-cohort analysis, no significant differences were observed in rates of any complication (all p ≥ 0.083). On multivariate regression analyses, RA was not associated with increased risk for any complication (p = 0.445), minor complications (p = 0.093), major complications (p = 0.758), unplanned reoperations (p = 0.355), unplanned readmissions (p = 0.799), or mortality (p = 0.579).ConclusionWith similar safety profiles, RA is a safe and reasonable alternative to GA when managing DRFs surgically. RA may be the preferred anesthetic technique for ORIF of DRFs in patients at high risk with GA, such as those with reactions to GA in the past or with significant cardiopulmonary risk factors.© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.

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