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- H Robert Superko, Kathryn M Momary, and Yonghong Li.
- Celera Corporation, Alameda, CA 94502, USA. Robert.Superko@celera.com
- Med. Clin. North Am. 2012 Jan 1; 96 (1): 123-39.
Abstract3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor medications, commonly referred to as statins, are among the most widely prescribed medications. Variation in individual response to statins concerning low-density lipoprotein cholesterol reduction, clinical event benefit, and side effects has been observed. Some of this variability is attributed to demographic and environmental issues, chief of which is compliance. A large portion of the individual response to statin therapy is attributed to single nucleotide polymorphisms that have recently been elucidated, several of which seem to have clinical utility.Copyright © 2012 Elsevier Inc. All rights reserved.
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