-
Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of tolmetin with aspirin in the treatment of osteo-arthritis of the knee.
- F O Müller, J A Gosling, and G H Erdmann.
- S. Afr. Med. J. 1977 May 28; 51 (22): 794-6.
AbstractA randomized, double-blind crossover study conducted on 55 patients showed tolmetin (Tolectin; Ethnor) (900 mg daily) to be as effective as aspirin (4 500 mg daily) in relieving the symptoms and signs of osteo-arthritis of the knee. Overall, aspirin produced significantly more side-effects, but the incidence of gastro-intestinal side-effects did not differ significantly. In almost every comparison tolmetin had the better score, but differences were not statistically significant; the only exception was the evaluation of the patients' well-being at mid-therapy, which significanlty favoured tolmetin.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..