-
Review Comparative Study
[Beta receptor blockers. Their role and therapeutic importance].
- R Regenthal, H Voigt, and R Preiss.
- Institut für Klinische Pharmakologie, Bereiches Medizin der Universität Leipzig.
- Z Gesamte Inn Med. 1991 Jan 1; 46 (1-2): 1-5.
AbstractFrom clinico-pharmacological view the present paper gives a survey of the important drug group of the beta-receptor blockers. While non-selective blockers effect a global depression of the sympathico-adrenergic activity of the organism, the beta 1-selective blockers are characterized by a dose-dependent preferred affinity to the cardiac and renal beta 1-receptors. Thus in low and moderate dosages undesired pulmonary, vascular and metabolic effects can be avoided. Main indications for beta-receptor blockers are the arterial hypertension, the coronary heart disease and the tachycardiac disturbances of the cardiac rhythm. Apart from the increase of the life-quality of the patient the prognosis improving effect in clinical long-term studies confirmed for several beta-receptor blockers should be used therapeutically.
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