• Thyroid · Aug 2004

    Case Reports

    Nondiabetic ketoacidosis caused by severe hyperthyroidism.

    • Emily T Wood and William B Kinlaw.
    • Department of Medicine, Division of Endocrinology and the Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, USA.
    • Thyroid. 2004 Aug 1; 14 (8): 628-30.

    AbstractSevere hyperthyroidism is not included in the traditional differential diagnosis of ketoacidosis. However, thyroid hormone has well-documented lipolytic effects on adipocytes and may also promote hepatic beta-oxidation. We present a case in which a woman with severe hyperthyroidism developed otherwise unexplained ketoacidosis during the acute phase of her illness. We propose that thyrotoxicosis was a significant contributor to ketoacidosis in this patient and that severe hyperthyroidism should be added to the differential diagnosis of ketoacidosis.

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