• Kathy-Ming Feng, Yi-Hao Chen, Jiann-Torng Chen, Li-Fan Lin, Wen-Chiuan Tsai, and Ching-Long Chen.
• National Defense Medical Center, Department of Ophthalmology, Tri-Service General Hospital, Taipei City 114, Taiwan.
• Medicina (Kaunas). 2021 May 28; 57 (6).

AbstractChoroid metastasis is the initial presentation of pleomorphic carcinoma (PC) of the lung. PC is classified as poorly differentiated non-small cell lung carcinoma. It has a tendency to metastasize early and has a poor response to chemotherapy, which often results in poor prognosis. We report the case of a 63-year-old woman with a one-month history of deteriorating vision in the left eye. Fundus examination, fluorescein angiography, indocyanine green angiography, and B-scan sonography demonstrated choroidal metastasis of the left eye. Positron emission tomography/computed tomography (PET/CT) revealed a tumor with increased uptake in the left upper lung. Subsequent bronchoscopic biopsy confirmed a pleomorphic carcinoma of the lungs. Choroid metastasis as an initial presentation of PC in the lung is rare. Usually, it represents the late course of disseminated disease with hematogenous spread. Prompt diagnosis is imperative for patients to immediately initiate treatment.

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