• Mihaela Camelia Tîrnovanu, Irina Daniela Florea, Adina Tănase, Bogdan Florin Toma, Elena Cojocaru, Carmen Ungureanu, and Ludmila Lozneanu.
• Department of Mother and Child Medicine, "Grigore. T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
• Medicina (Kaunas). 2021 May 27; 57 (6).

AbstractOvarian malignant germ cell tumors (OMGCT) represent less than 10% of all ovarian tumors. Dysgerminoma is the most common malignant primitive germ cell tumor in young women, known for its curability and low propensity to invade and metastasize when diagnosed early. Herein, we report an unusual type of ovarian dysgerminoma (OD) metastasis with a brief review of the literature, lacking similar reported cases. To our knowledge, although there are several case reports of dysgerminoma metastases with variable anatomic location and presentation, vaginal metastasis has not been previously described. The local or systemic relapse together with local and distant metastasis is considered as an independent predictor of poor survival in patients with OD. In light of the absence of mutations status, our patient successfully responded to therapy. Currently, the patient remains in clinical remission. A specific follow-up plan is ongoing knowing that ovarian dysgerminomas tend to recur most often in the first 2-3 years after treatment.

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