• Ming-Xing He, Cong-Jie Lei, Dong-Ling Zhong, Qi-Cen Liu, Hong Zhang, Yi-Jie Huang, Yu-Xi Li, Xiao-Bo Liu, Juan Li, Rong-Jiang Jin, and Li Wan.
• School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Sichuan.
• Medicine (Baltimore). 2019 Aug 1; 98 (33): e16786e16786.

IntroductionTo investigate the effectiveness and safety of electromyography (EMG) biofeedback therapy in improving motor dysfunction among children with cerebral palsy (CP).Methods And AnalysisThe following databases will be searched: PubMed, EMBASE, ScienceDirect, the Cochrane Library, China National Knowledge infrastructure (CNKI), Technology Periodical Database (VIP), WanFang Data and China Biology Medicine (CBM) from inception to June 2019. All relevant randomized controlled trials (RCTs) utilizing EMG biofeedback therapy for CP will be included. The main outcome is the Gross Motor Function Measure (GMFM). Additional outcomes such as the Modified Ashworth Scale (MAS), Integral Electromyogram (iEMG), Composite Spasticity Scale (CSS), passive range of motion (PROM) or other related outcomes will be included, adverse effects of EMG biofeedback therapy and comparators will also be included. Two reviewers will screen studies, extract data and assess quality independently. Review Manager 5.3 will be used to assess the risk of bias, data synthesis, and subgroup analysis.Ethics And DisseminationThis systematic review does not require formal ethical approval because all data will be analyzed anonymously. Results will provide a general overview and evidence concerning the effectiveness and safety of EMG biofeedback therapy for children with CP. The findings of this systematic review will be disseminated through peer-reviewed publications or conference presentations.

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