• Seminars in perinatology · Feb 2019

    Review

    Medical management of postpartum hemorrhage: An update.

    • Luis D Pacheco, George R Saade, and Hankins Gary D V GDV Department of Anesthesiology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0587, United States..
    • Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0587, United States; Department of Anesthesiology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0587, United States. Electronic address: ldpachec@utmb.edu.
    • Semin. Perinatol. 2019 Feb 1; 43 (1): 22-26.

    AbstractObstetrical hemorrhage is the most common cause of maternal mortality worldwide. Together with adequate surgical control and judicious transfusion of blood products, the use of pharmacological agents (e.g., tranexamic acid) and clotting factor concentrates (e.g., fibrinogen concentrates and prothrombin complex concentrates) results in improved hemostasis and decreased bleeding-associated mortality. Guidance in the administration of these agents with the use of viscoelastic testing will likely become standard of care in the near future.Copyright © 2018. Published by Elsevier Inc.

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