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- Keith Azevedo, Molly Johnson, Michael Wassermann, and Jessica Evans-Wall.
- Departments of Emergency and Internal Medicine, University of New Mexico Hospital, MSC11 6025, 1 University of New Mexico, Albuquerque, NM 87131, USA. Electronic address: kazevedo@salud.unm.edu.
- Crit Care Clin. 2021 Jul 1; 37 (3): 501-516.
AbstractOver the last 2 decades, prescription and nonprescription substance use has significantly increased. In this article, 3 particular drug classes-opioids, sedatives, and hypnotics-are discussed. For each class, a brief history of the agent, a description of relevant pharmacology, the clinical presentation of overdose, the management of specific drug overdoses, and a summary of salient points are presented. The intent is to provide a clinically relevant and comprehensive approach to understanding these potential substance exposures in order to provide a framework for management of opioid, sedative, and hypnotic overdoses.Copyright © 2021 Elsevier Inc. All rights reserved.
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