• Internal medicine journal · May 2021

    Hyperferritinaemia and iron overload in Asian patients: lessons from an Australian tertiary centre experience.

    • Danny Con and Amanda J Nicoll.
    • Department of Gastroenterology, Eastern Health, Melbourne, Victoria, Australia.
    • Intern Med J. 2021 May 1; 51 (5): 802805802-805.

    AbstractIron overload is described in Asian patients but presents with a different phenotype and genotype compared to Caucasian patients. We retrospectively identified 64 Asian patients and compared them to 64 matched non-Asian patients with at least one episode of serum ferritin >500 μg/L. Of the Asian patients, one (1.6%) had proven iron overload, while other common causes of hyperferritinaemia included recent blood transfusion (47%), acute infection (11%) and haematological malignancy (8%). A greater proportion of non-Asian patients had hyperferritinaemia secondary to high alcohol intake. Iron overload is rare in Asians and unexplained hyperferritinaemia in Asian patients is more likely to be due to other factors.© 2021 Royal Australasian College of Physicians.

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