• New Horiz · Nov 1996

    Use of near-infrared spectroscopy to monitor tissue oxygenation.

    • D E Taylor and S G Simonson.
    • Pulmonary and Critical Care Medicine Division, University of Texas Health Sciences Center, Houston 77030, USA.
    • New Horiz. 1996 Nov 1; 4 (4): 420-5.

    AbstractNear-infrared spectroscopy (NIRS) is a relatively new tool that allows continuous noninvasive monitoring of in vivo oxygenation in selected tissues such as muscle and brain. Since hemoglobin, myoglobin, and cytochrome c oxidase are the only biological compounds to exhibit variable absorption of near-infrared (NIR) light in response to changes in oxygen availability, NIRS can determine changes in tissue oxygenation. NIRS can measure regional blood volume, local oxyhemoglobin and deoxyhemoglobin contents, and reduction-oxidation state of cellular mitochondrial cytochrome a, a3. As a comprehensive monitor of regional oxygen metabolism, NIRS has been applied in certain clinical and research settings. Despite technical limitations and the lack of definite "gold standards" to allow validation of results, NIRS remains a promising technology with applications in both the critical care environment and the research laboratory studying mechanisms of oxygen metabolism.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…