• Yaying Sun, Shaohua Liu, Shiyi Chen, and Jiwu Chen.
• Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
• Am J Sports Med. 2018 Mar 1; 46 (3): 663-670.

BackgroundCorticosteroid injection is a common treatment for frozen shoulder, but controversy still exists regarding the injection site with the best outcome.HypothesisTo treat the frozen shoulder in the freezing stage with corticosteroid injection, a single injection into the rotator interval (RI) could yield better effects in terms of improvement in pain, passive range of motion (ROM), and function than would an injection into the intra-articular (IA) or subacromial (SA) space.Study DesignRandomized controlled trial; Level of evidence, 1.MethodsPatients with primary frozen shoulder in the freezing stage were randomized into 3 groups: RI injection, IA injection, or SA injection with corticosteroid. Clinical outcomes were documented at baseline and at 4, 8, and 12 weeks after intervention, including visual analog scale (VAS) for pain; passive ROM measurements, including external rotation, internal rotation, forward flexion, and abduction; and evaluation with the Disability of Arm, Hand, and Shoulder (DASH) score and Constant score.ResultsThere were no significant differences in the basic properties of the 3 groups (27 in RI group, 24 in IA group, and 26 in SA group) before injection. Improvements in pain VAS, passive ROM, Constant score, and DASH score were faster and significant in the RI group from 4 weeks after injection, followed by those in the IA group. Passive ROM decreased and DASH score did not change significantly in the SA group, although pain VAS and Constant score improved significantly.ConclusionTo treat frozen shoulder in the freezing stage with corticosteroid injection, a single injection into the RI yielded better effects in terms of improvement in pain, passive ROM, and function than did injections into the IA or SA space.

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