• Cheol-Woong Yu, Hyun-Jong Lee, Jon Suh, Nae-Hee Lee, Sang-Min Park, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Seung Hyuk Choi, Hyeon-Cheol Gwon, Sang-Hoon Lee, Yeon Hyeon Choe, Sung Mok Kim, and Jin-Ho Choi.
• From the Department of Medicine, Korea University Anam Hospital, Seoul (C.-W.Y.); Department of Internal Medicine, Sejong General Hospital, Bucheon, Korea (H.-J.L.); Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Korea (J.S., N.-H.L.); Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital (S-M.P.); and Department of Emergency Medicine (J.-H.C.), Department of Medicine (J.-H.C., T.-K.P., J.-H.Y., Y.-B.S., J.-Y.H., S.-H.C., H.-C.G., S.-H.L.), and Department of Radiology (Y.-H.C., S.-M.K.), Cardiovascular Imaging Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jhchoimd@gmail.com ycw717@naver.com.
• Circ Cardiovasc Imaging. 2017 Apr 1; 10 (4).

BackgroundWe developed a model that predicts difficulty of percutaneous coronary intervention for coronary chronic total occlusion (CTO) using coronary computed tomographic angiography.Methods And ResultsA total of 684 CTO lesions with preprocedural computed tomographic angiography were enrolled from 4 centers. Data were randomly divided into derivation and validation datasets at 2:1 ratio. The end point was successful guidewire crossing ≤30 minutes, which was met in 50%. The KCCT (Korean Multicenter CTO CT Registry) score was developed based on independent predictors identified by multivariable analysis, which were proximal blunt entry, proximal side branch, bending, occlusion length ≥15 mm, severe calcification, whole luminal calcification, reattempt, and ≥12 months or unknown duration of occlusion. The KCCT score was compared with the other prediction scores, including angiography-based J-CTO, PROGRESS-CTO, CL-score, and CT-based CT-RECTOR. The probability of guidewire crossing ≤30 minutes declined consistently from 100% to 0% according to the KCCT score (P<0.01, all). The KCCT score showed higher discriminative performance compared with the other scoring systems (c-statistics=0.78 versus 0.65-0.72, P<0.001, all). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of a KCCT score of <4 for guidewire crossing ≤30 minutes was 70%, 68%, 72%, 73%, and 70%, respectively. The KCCT score also showed consistent results with procedural success (P<0.05, all). These results could be reproduced in validation data set (P<0.05, all).ConclusionsKCCT scoring could predict successful guidewire crossing ≤30 minutes and also procedural success. KCCT scoring may enable noninvasive grading difficulty of CTO percutaneous coronary intervention.© 2017 American Heart Association, Inc.

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