-
Revista médica de Chile · Feb 2005
[Critical appraisal: enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis].
- Juan Jorge Manríquez and Luz María Letelier.
- Unidad de Medicina Basada en Evidencia, Chile.
- Rev Med Chil. 2005 Feb 1; 133 (2): 250-2.
ObjectiveTo compare the safety and clinical outcomes of enteral and parenteral nutrition in patients with acute pancreatitis.Data SourcesMedline, Embase, Cochrane controlled trials register, and citation review of relevant primary and review articles.Study SelectionRandomized controlled studies that compared enteral nutrition with parenteral nutrition in patients with acute pancreatitis. From 117 articles screened, six were identified as randomized controlled trials and were included for data extraction.Data ExtractionSix studies with 263 participants were analyzed. Descriptive and outcome data were extracted. Main outcome measures were infections, complications other than infections, operative interventions, length of hospital stay, and mortality. The metaanalysis was performed with the random effects model.Data SynthesisEnteral nutrition was associated with a significantly lower incidence of infections (relative risk 0.45; 95% confidence interval 0.26 to 0.78, P= 0.004), reduced surgical interventions to control pancreatitis (0.48, 0.22 to 1.0, P= 0.05), and a reduced length of hospital stay (mean reduction 2.9 days, 1.6 days to 4.3 days, P <0.001). There were no significant differences in mortality (relative risk 0.66, 0.32 to 1.37, P = 0.3) or non-infectious complications (0.61, 0.31 to 1.22, P= 0.16) between the two groups of patients.ConclusionsEnteral nutrition should be the preferred route of nutritional support in patients with acute pancreatitis.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*
,_underline_
or**bold**
. - Superscript can be denoted by
<sup>text</sup>
and subscript<sub>text</sub>
. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3.
, hyphens-
or asterisks*
. - Links can be included with:
[my link to pubmed](http://pubmed.com)
- Images can be included with:
![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
- For footnotes use
[^1](This is a footnote.)
inline. - Or use an inline reference
[^1]
to refer to a longer footnote elseweher in the document[^1]: This is a long footnote.
.