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Urol. Clin. North Am. · Feb 2020
ReviewBacillus Calmette-Guérin Salvage Therapy: Definitions and Context.
- Badrinath R Konety, Vikram M Narayan, and Colin P N Dinney.
- Department of Urology, University of Minnesota, 420 Delaware Street Southeast, MMC 394, Mayo B536, Minneapolis, MN 55455, USA. Electronic address: brkonety@umn.edu.
- Urol. Clin. North Am. 2020 Feb 1; 47 (1): 1-4.
AbstractHigh-risk non-muscle invasive bladder cancer is marked by frequent disease recurrences and risk of stage progression, contributing to high surveillance, treatment-related costs, and patient anxiety. Although the mainstay of high-risk non-muscle invasive bladder cancer clinical management remains transurethral resection followed by intravesical bacillus Calmette-Guérin (BCG), patients who develop BCG-unresponsive disease have few salvage options outside of a radical cystectomy with pelvic lymphadenectomy. This article provides a historical context relevant to the development of the BCG-unresponsive definition, an overview of current clinical trial expectations, and an introduction to this issue of Urologic Clinics.Copyright © 2019 Elsevier Inc. All rights reserved.
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