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Catheter Cardiovasc Interv · Sep 2009
Randomized Controlled Trial Multicenter Study Comparative StudyPercutaneous versus surgical revascularization for multivessel coronary artery disease: a single center 10 year follow-up of SOS trial patients.
- Pawel Buszman, Szymon Wiernek, Radoslaw Szymanski, Bozena Bialkowska, Piotr Buszman, Wojciech Fil, Rodney Stables, Andrzej Bochenek, Jack Martin, and Michal Tendera.
- Upper Silesian Medical Center, 45-47 Ziolowa, 40-635 Katowice, Poland. pbuszman@ka.onet.pl
- Catheter Cardiovasc Interv. 2009 Sep 1; 74 (3): 420-6.
ObjectivesTo compare 10 year outcomes including death, left ventricular ejection fraction (LVEF), major adverse cardiovascular and cerebrovascular events (MACCE), repeat revascularization (RR), and severity of angina (CCS) after randomization to stent supported percutaneous coronary intervention (PCI) or surgical revascularization (CABG) in a single center participating in the SOS trial.BackgroundRandomized studies show increased RR following PCI, but otherwise similar results to CABG in selected mutlivessel disease patients with up to 5 year follow up. There is no 10 year data available.Materials And MethodsThe analysis involved 100 patients randomized into the SOS study in Poland.ResultsPatients were well matched for baseline demographic and angiographic characteristics. During 9.6 +/- 0.85 year observation, there was no significant difference between groups for survival, CCS, and LVEF. Increased RR occurred following PCI; 21 (42%) vs. 9 (18%), P < 0.05. As a consequence, the MACCE was also significantly higher following PCI; 36 (72%) vs. 28 (56%), P < 0.05. Excess RR predominantly occurred in the first year and diminished over time with numerically less RR following PCI from year 5 to 10; 2 (4%) vs. 7 (14%), P = ns.ConclusionsThese findings suggest that patients with multivessel coronary artery disease technically suitable for either stent supported PCI or CABG have very similar 10 year outcomes with respect to mortality, angina class, LVEF, and MACCE other than RR. Excess RR following PCI predominantly occurs in early years and is numerically lower following PCI in years 5-10. This underscores the need for longer-term follow up from randomized trials.2009 Wiley-Liss, Inc.
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