• Gaspar Manuel Parra-Bracamonte, Nicolas Lopez-Villalobos, and Francisco E Parra-Bracamonte.
• Centro de Biotecnología Genómica-Instituto Politécnico Nacional, Reynosa, Mexico. Electronic address: gparra@ipn.mx.
• Ann Epidemiol. 2020 Dec 1; 52: 93-98.e2.

PurposeThe purpose of this study was to assess clinical characteristics and risk factors for mortality of patients with coronavirus disease 2019 (COVID-19) from Mexico, given that it currently is in active community transmission.MethodsMultivariate logistic regression model and Kaplan-Meier survival curves were fitted to study odds of death of characteristics and comorbidities in patients with COVID-19 in Mexico.ResultsAge, sex, and the most frequent comorbidities diabetes, obesity, and hypertension were significantly associated to the risk of death by COVID-19 (P < .0001). Smoking habit was not identified as a risk factor for death. Less-frequent comorbidities such as chronic obstructive pulmonary disease, chronic kidney disease, and patients with immunosuppressed conditions also showed a significant risk for death (P < .0001). Hospitalized patients and those with pneumonia had serious risks for mortality (P < .0001), and more attention to specific conditions might be considered during clinical admission.ConclusionsA more vulnerable positive patient is depicted by a male patient, older than 41 years, which increases their risk with more prevalent comorbidities such as diabetes, hypertension, and obesity. Some implications on outcomes are discussed.Copyright © 2020 Elsevier Inc. All rights reserved.

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