• J Surg Oncol · Mar 2003

    Review

    Current management of melanoma: benefits of surgical staging and adjuvant therapy.

    • Kelly M McMasters and Susan M Swetter.
    • Division of Surgical Oncology, University of Louisville, J. Graham Brown Cancer Center, Louisville, Kentucky 40202, USA. kelly.mcmasters@nortonhealthcare.org
    • J Surg Oncol. 2003 Mar 1; 82 (3): 209-16.

    AbstractIssues regarding appropriate management of stage I to III melanoma are addressed. Accurate surgical staging is critical to identifying patients who can benefit from therapeutic lymph node dissection and adjuvant therapy. Patients with primary tumors > or = 1 mm thick are appropriate candidates for sentinel lymph node biopsy, and node-positive patients benefit from therapeutic lymphadenectomy. Although the overall survival benefit of high-dose interferon has been questioned, the weight of evidence supports the use of adjuvant therapy in patients with stage IIB and III disease.Copyright 2003 Wiley-Liss, Inc.

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