• Dtsch. Med. Wochenschr. · Jun 2021

    [Lung involvement in rheumatic diseases].

    • Hans Bastian and Andreas Krause.
    • Abteilung Innere Medizin, Rheumatologie, Klinische Immunologie und Osteologie, Immanuel-Krankenhaus Berlin, Standort Berlin-Wannsee.
    • Dtsch. Med. Wochenschr. 2021 Jun 1; 146 (11): 752-756.

    AbstractLung involvement is one of the most frequent organ manifestation in rheumatic diseases (CTD-ILD). Especially patients with rheumatoid arthritis, systemic sclerosis, and idiopathic inflammatory myopathies are affected. Interstitial lung diseases (ILD) are still associated with significant morbidity and mortality. The last years have brought advances in management and treatment of ILDs. Methotrexate is probably not a significant cause of lung disease in rheumatoid arthritis but might even delay the presentation of interstitial lung disease (ILD). Tocilizumab could be a treatment option in SSc-ILD, despite the limitations of the current studies. For Systemic Sclerosis-ILD (SSc-ILD) and progressive fibrosing ILD, antifibrotic therapy with nintedanib is now approved.Thieme. All rights reserved.

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