• Bernd Panholzer, Katrin Meckelburg, Katharina Huenges, Grischa Hoffmann, Michael von der Brelie, Nils Haake, Kevin Pilarczyk, Jochen Cremer, and Assad Haneya.
• 1 Department of Cardiovascular Surgery, University of Schleswig-Holstein, Campus Kiel, Kiel, Germany.
• Perfusion. 2017 Sep 1; 32 (6): 495-500.

ObjectivesOver the last decade, extracorporeal membrane oxygenation (ECMO) has become a promising option for patients with severe acute respiratory distress syndrome (ARDS). In this single-center observational cohort study, data from a patient group with severe ARDS treated with ECMO was analyzed.MethodsData from 46 patients [median age 54 years (18 to 72), male: 65.2%] were evaluated retrospectively between January 2009 and September 2015.ResultsDiagnosis leading to ARDS was pneumonia in 63.1% of the patients. The median SOFA Score was 13 (10 to 19) and the median LIS was 3.5 (2.67 to 4). The median duration of ECMO support was 12 days (1 to 86). Twenty-eight patients (60.9%) were successfully weaned from ECMO and 22 patients survived (47.8%). Non-survivors needed significantly more frequent renal replacement therapy (37.5% vs. 18.2%; p<0.01) and transfusion of red blood cell concentrates [0.4 units (0.3 to 1.2) vs. 0.9 units (0.5 to 1.6); p<0.01] during ECMO support compared to patients who survived.ConclusionThis report suggests that ECMO currently allows treatment of severe ARDS with presumed improved survival. The incidence rate of acute kidney injury and transfusion are associated with adverse outcomes.

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