• J Neuroophthalmol · Sep 2011

    Case Reports

    Early diagnosis of Horner syndrome using topical apraclonidine.

    • Johnathan Cooper-Knock, Irene Pepper, Timothy Hodgson, and Basil Sharrack.
    • Department of Neurology, Sheffield Teaching Hospitals NHS Trust, University of Sheffield, Sheffield, United Kingdom. j.cooper-knock@sheffield.ac.uk
    • J Neuroophthalmol. 2011 Sep 1; 31 (3): 214-6.

    AbstractThe diagnosis of Horner syndrome (HS) using apraclonidine eye drops is an alternative to the use of topical cocaine drops. A number of reports have described the efficacy of apraclonidine testing, but there is some debate over its sensitivity in the acute setting. We describe a patient with HS secondary to carotid dissection who had a positive response to apraclonidine 3 hours after the onset of symptoms. The case is made for a larger study of apraclonidine use to determine its true sensitivity and specificity, identify confounding factors, and redefine the criteria for positive testing.

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