• Muscle & nerve · Jul 2011

    Multicenter Study Comparative Study

    Median nerve changes following steroid injection for carpal tunnel syndrome.

    • Michael S Cartwright, David L White, Samantha Demar, Ethan R Wiesler, Thomas Sarlikiotis, George D Chloros, Joon Shik Yoon, Sun Jae Won, Joseph A Molnar, Anthony J Defranzo, and Francis O Walker.
    • Department of Neurology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157, USA. mcartwri@wfubmc.edu
    • Muscle Nerve. 2011 Jul 1; 44 (1): 25-9.

    IntroductionNeuromuscular ultrasound is a painless, radiation-free, high-resolution imaging modality for assessment of the peripheral nervous system. The purpose of this study was to use neuromuscular ultrasound to assess the changes that occur in the median nerve after steroid injection for carpal tunnel syndrome (CTS).MethodsUltrasound and nerve conduction studies were performed at baseline and 1 week, 1 month, and 6 months after steroid injection in 19 individuals (29 wrists) with CTS.ResultsSignificant changes were noted in median nerve cross-sectional area (P < 0.001), mobility (P = 0.001), and vascularity (P = 0.042) at the distal wrist crease after steroid injection, and the nerve cross-sectional area correlated with symptom score and electrodiagnostic parameters. Changes in the ultrasonographic parameters were seen within 1 week of injection.ConclusionsThese findings suggest neuromuscular ultrasound is potentially helpful for the assessment of individuals undergoing treatment for CTS, as typical changes can be expected after successful treatment injection.Copyright © 2011 Wiley Periodicals, Inc.

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