Unusual onset of venous thromboembolism and heparin-induced

Blood Coagul. Fibrinolysis · Jan 2010

Case Reports

Unusual onset of venous thromboembolism and heparin-induced thrombocytopenia in a patient with essential thrombocythemia.

Essential thrombocythemia is a hematological disorder characterized by clonal hemopoiesis in the bone marrow and increased number of circulating platelets. It is usually discovered accidentally at the time of routine blood examinations or can become clinically evident with either thrombotic or hemorrhagic complications. In the present article, we describe the case of a 66-year-old woman with pneumonia due to Pneumocystis carinii, who experienced deep vein thrombosis and pulmonary embolism during hospitalization with a subsequent heparin-induced thrombocytopenia. Bone marrow examination performed after clinical improvement revealed the patient to be affected by essential thrombocythemia.

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- Mario Lapecorella, Alessandro Lucchesi, Mauro Di Ianni, Mariasanta Napolitano, Gino Coletti, Gabriella Di Leonardo, Luigi Dell'Orso, Remo Barnabei, and Guglielmo Mariani.
- Centro Emofilia e Trombosi, Unità Operativa Medicina Interna 2, Ematologia, Università de L'Aquila, Ospedale San Salvatore, L'Aquila, Italy. emofilia.aq@cc.univaq.it
- Blood Coagul. Fibrinolysis. 2010 Jan 1; 21 (1): 85-90.
AbstractEssential thrombocythemia is a hematological disorder characterized by clonal hemopoiesis in the bone marrow and increased number of circulating platelets. It is usually discovered accidentally at the time of routine blood examinations or can become clinically evident with either thrombotic or hemorrhagic complications. In the present article, we describe the case of a 66-year-old woman with pneumonia due to Pneumocystis carinii, who experienced deep vein thrombosis and pulmonary embolism during hospitalization with a subsequent heparin-induced thrombocytopenia. Bone marrow examination performed after clinical improvement revealed the patient to be affected by essential thrombocythemia.

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Unusual onset of venous thromboembolism and heparin-induced thrombocytopenia in a patient with essential thrombocythemia.

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