• F Henríquez, A Rodríguez, C Mora, E Sánchez-Deig, M Macía, and J Navarro.
• Servicio de Nefrología, Hospital Universitario Nuestra Señora de Candelaria, Carreteral del Rosario 145.
• Nefrologia. 2006 Jan 1; 26 (6): 734-7.

AbstractThrombocytopenia is a potential complication of heparin therapy. There are two forms of heparin-induced thrombocytopenia (HIT). Type-I HIT is characterized by a mild decrease in platelet count that occurs within the first 2-4 days after heparin initiation. The platelet count often returns to normal without stop heparin treatment. The mechanism of thrombocytopenia appears to be due to a direct effect of heparin on platelet activation. The second form (type-II) is an immune-mediated disorder characterized by severe thrombocytopenia, which may include both arterial and venous thrombosis. We present a case of type-II HIT occurred in a hemodialysis patient resulting in acute pulmonary embolism and peripheral venous thrombosis, and review the literature.

43 keywords...

hide…