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Review Case Reports
[Heparin-induced thrombocytopenia in hemodialysis. Case report and review of the literature].
- F Henríquez, A Rodríguez, C Mora, E Sánchez-Deig, M Macía, and J Navarro.
- Servicio de Nefrología, Hospital Universitario Nuestra Señora de Candelaria, Carreteral del Rosario 145.
- Nefrologia. 2006 Jan 1; 26 (6): 734-7.
AbstractThrombocytopenia is a potential complication of heparin therapy. There are two forms of heparin-induced thrombocytopenia (HIT). Type-I HIT is characterized by a mild decrease in platelet count that occurs within the first 2-4 days after heparin initiation. The platelet count often returns to normal without stop heparin treatment. The mechanism of thrombocytopenia appears to be due to a direct effect of heparin on platelet activation. The second form (type-II) is an immune-mediated disorder characterized by severe thrombocytopenia, which may include both arterial and venous thrombosis. We present a case of type-II HIT occurred in a hemodialysis patient resulting in acute pulmonary embolism and peripheral venous thrombosis, and review the literature.
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