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Microvascular research · May 2020
Comparative StudyLaser speckle contrast imaging, the future DBF imaging technique for TRP target engagement biomarker assays.
- Dorien Bamps, Laura Macours, Linde Buntinx, and Jan de Hoon.
- Center for Clinical Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, KULeuven, Leuven, Belgium. Electronic address: dorien.bamps@kuleuven.be.
- Microvasc. Res. 2020 May 1; 129: 103965.
AbstractA comparison was made between the established laser Doppler imaging (LDI) technique and the more recently developed laser speckle contrast imaging (LSCI) method to measure changes in capsaicin- and cinnamaldehyde-induced dermal blood flow (DBF) as an indicator of TRPV1 and TRPA1 activation, respectively.Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.
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