-
- Ryota Ushio, Masaki Yamamoto, Atsushi Miyasaka, Tatsuya Muraoka, Hiromi Kanaoka, Hironori Tamura, Ayami Kaneko, Ami Izawa, Nobuyuki Hirama, Shuhei Teranishi, Saki Manabe, Tatsuya Inoue, Kunihiko Shibata, Yasuyuki Sugiura, Makoto Kudo, and Takeshi Kaneko.
- Respiratory Disease Center, Yokohama City University Medical Center, Japan.
- Intern. Med. 2021 Nov 15; 60 (22): 3593-3598.
AbstractA 58-year-old man was diagnosed with lung adenocarcinoma with a tumor proportion score of 10%. After six cycles of second-line chemotherapy with nivolumab, he achieved a complete response (CR) but developed uveitis and sensorineural hearing disorder, which were consistent with Vogt-Koyanagi-Harada (VKH)-like syndrome. Simultaneously, pituitary adrenocortical insufficiency was identified. Nivolumab discontinuation and systemic corticosteroid administration resolved these immune-related adverse events (irAEs). The patient has maintained a CR without any chemotherapy for approximately two years. We herein report a patient with a long-term progression-free survival despite chemotherapy discontinuation due to irAEs, including VKH-like syndrome, which were appropriately managed.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..