• Internal medicine · Nov 2021

    Case Reports

    A Case of Yellow Nail Syndrome in Which Intranodal Lymphangiography Contributed to the Diagnosis.

    • Takahiro Uchida, Yoshitaka Uchida, Masao Takahashi, Kenji Masaki, Hideaki Sato, Hidetoshi Iemura, Shun Shinomiya, Hidetoshi Nakamura, and Makoto Nagata.
    • Department of Respiratory Medicine, Saitama Medical University Hospital, Japan.
    • Intern. Med. 2021 Nov 15; 60 (22): 3599-3603.

    AbstractYellow nail syndrome (YNS) is a rare disease comprising the clinical triad of yellow nail discoloration, pleural effusion, and lower limb lymphedema. We encountered a difficult-to-treat case of YNS in which the diagnosis was finally made based on intranodal lymphangiography. An 84-year-old man was admitted to our hospital with pleural effusion and yellow-green discoloration of the nails, accompanied by onychomycosis and limb lymphedema. Intranodal lymphangiography revealed a slow contrast flow and narrowing of the thoracic duct, suggesting lymphatic duct dysplasia and leading to the diagnosis of YNS.

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