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Case Reports
Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure.
- Shintaro Fujii, Kazuhiro Horiuchi, Yuki Oshima, Katsuki Eguchi, Azusa Nagai, Ikuko Iwata, Masaaki Matsushima, and Ichiro Yabe.
- Department of Neurology, Hakodate Municipal Hospital, Japan.
- Intern. Med. 2021 Dec 1; 60 (23): 3801-3804.
AbstractA 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial antibodies (AMA). Muscle histopathological findings included immune-mediated necrotizing myopathy, so she was diagnosed with inflammatory myopathy associated with AMA. After treatment with corticosteroids and noninvasive positive pressure ventilation, her symptoms improved. If a diagnosis of type II respiratory failure is difficult, inflammatory myopathy associated with AMA should be considered as a differential diagnosis.
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