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Frontiers of medicine · Mar 2013
Case ReportsA case of thymic Langerhans cell histiocytosis with diabetes insipidus as the first presentation.
- Xiaoyan Chen, Xiaochun Huang, Yuan Qiu, Hanzhang Chen, Yingyu Fu, and Xinchun Li.
- Department of Endocrinology, First Affiliated Hospital of Guangzhou Medical College, Guangzhou, 510120, China. gzscxy@126.com
- Front Med. 2013 Mar 1; 7 (1): 143-6.
AbstractLangerhans cell histiocytosis (LCH) is an idiopathic group of reactive proliferative diseases linked to aberrant immunity, pathologically characterized by clonal proliferation of Langerhans cells. LCH rarely involves the thymus. We report a case of thymic LCH with diabetes insipidus as the first presentation, without evidence of myasthenia gravis and without evidenced involvement of the skin, liver, spleen, bones, lungs and superficial lymph nodes. This present case may have important clinical implications. In screening for LCH lesions, attention should be attached to rarely involved sites in addition to commonly involved organs. Follow-up and imageological examination are very important to a final diagnosis.
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